ABSTRACT
Objective To establish a standard anti-viral treatment for chronic HBV carriers. Methods With reference to the domestic and abroad literatures, the diagnostic and therapeutic standards were set and prepared to be verified. ResultsThe diagnostic standards included:(①ALT 30 -40 IU/L: add 2 scores. (②Age:30 -39 ,add 1 score; ≥40,add 2 scores. (③Ultrasound examination: obviously abnormal,add 1 score;deteriorated during follow up:add 2 scores. ④Fibrosis markers positive: add 1 score. (⑤History of HCC in vertical relatives:add 1 score. ⑥ Existence of conditions which can induced elevation of ALT such as fatty liver or alcoholic liver or BMI ＞ 23 kg/m2,minus 2 scores. The therapeutic standards included:(①≥5 scores: should be treated;(②3 -4 scores: may be treated or just follow up;(③≤2 scores;follow up and reexamine every 6 months. ConclusionsThe above standards are preliminary suggestions which should be checked and rectified by liver biopsy to achieve a more accurate and more practical standard.
ABSTRACT
Objective To study the relationship between the renal hemodynamic changes and the course of the liver diseases and demonstrate weather the renal blood flow resistance index(RI)could be a useful index used to predict the hepatorenal syndrome(HRS)in the decompensated cirrhosis.Methods Select 41 patients diagnosed as decompensated cirrhosis from the patients examined by color Doppler ultrasonography at the Infectious Disease Department of Peking University First Hospital from April 2004 to July 2006.Test the serum creatinine,serum total bilirubin and INR,confirm the cause of the cirrhosis,and then calculate the MELD score.Detect by color Doppler ultrasonography to get RI.Results No correlation was found between RI and the patients's age,hemoglobin and systolic pressure.RI was found to be directly related with MELD score(r= 0.502,P